In The follow-up of a type 2 diabetes patient, it is generally accepted to consume their own insulin reserves over a period of 10-12 years, and after this period, signs of organ damage begin to manifest themselves. This is the period when patients generally apply for treatment. 22 Mayıs 2013 https://www.hurriyet.com.tr/advertorial/prof-dr-alper-celik-uyariyor-diyabet-ve-agiz-sagligi-problemleri-42156519