CRISPR-based gene drives offer promising prospects for controlling disease-transmitting vectors and agricultural pests. A significant challenge for successful suppression-type drive is the rapid evolution of resistance alleles. One approach to mitigate the development of resistance involves targeting functionally constrained regions using multiple gRNAs. https://www.roneverhart.com/2010-FORD-FUSION-Alternator-Assembly-2-5l-125K-Miles-FWD-Automatic-Trans-G/