Aim: to compare changes in the ADAMTS-13 metalloproteinase/von Willebrand factor (vWF) axis in pregnant women with spontaneous or following in vitro fertilization (IVF) singleton and bichorial biamniotic pregnancies. Materials and Methods. A prospective observational randomized controlled trial was conducted. https://parisnaturalfoodes.shop/product-category/quercetin-lipomicel/